Background:ST18 (suppression of tumorigenicity 18), also known as ZNF387 ((zinc finger protein 387), is a 1,047 amino acid nuclear protein that is expressed at low levels in heart, liver, kidney, skeletal muscle, pancreas, testis, ovary and prostate. Containing six C2HC-type zinc fingers and an SMC domain, ST18 is a repressor protein that binds to DNA sequences containing a specific bipartite element. ST18 is considered a transcription factor that represses basal transcription activity from target promoters and Inhibits colony formation in cultured breast cancer cells.
仕様
Synonyms:KIAA0535,St18,ST18,suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein),Suppression of tumorigenicity 18 protein,Suppression of tumorigenicity protein 18,Zinc finger protein 387,Znf387
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:IHC,ELISA
Concentration:0.8mg/mL
Immunogen:Recombinant protein of human ST18
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:25-1:100
Swissprot:O60284
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Stem cells