Background:The protein encoded by this gene is a member of the serpin family of proteinase inhibitors. Members of this family maintain homeostasis by neutralizing overexpressed proteinase activity through their function as suicide substrates. This protein inhibits the neutrophil-derived proteinases neutrophil elastase, cathepsin G, and proteinase-3 and thus protects tissues from damage at inflammatory sites. Alternative splicing results in multiple transcript variants.
仕様
Synonyms:Anti elastase,EI,ELANH2,Epididymis luminal protein 57,HEL57,ILEU,LEI,Leukocyte elastase inhibitor,M/NEI,MNEI,Monocyte/neutrophil elastase inhibitor,Peptidase inhibitor 2,Pi-2,PI2,Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 1,Serpin B1,Serpin peptidase inhibitor clade B (ovalbumin) member 1,serpinb1
Host:Rabbit
Reactivity:Human,Mouse
Applications:IHC,ELISA
Concentration:0.3mg/mL
Immunogen:Recombinant protein of human SERPINB1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:25-1:100
Swissprot:P30740
Isotype:IgG
Research Areas:Cancer, Cell Biology, Cardiovascular