Background:This gene encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome.
仕様
Synonyms:ATOX1,ATOX1,ATX1,ATX1 antioxidant protein 1 homolog (yeast),ATX1 antioxidant protein 1 homolog,Copper transport protein,Copper transport protein ATOX1,HAH1,Metal transport protein,Metal transport protein ATX1,MGC138453,MGC138455
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:IHC,ELISA
Concentration:0.4mg/mL
Immunogen:Recombinant protein of human ATOX1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:25-1:100
Swissprot:O00244
Isotype:IgG
Research Areas:Cancer, Cell Biology, Metabolism, Signal transduction