Background：This gene encodes a member of the RSK （ribosomal S6 kinase） family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase （MAPK） signaling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
仕様
Synonyms：90 kDa ribosomal protein S6 kinase 1,dJ590P13.1 （ribosomal protein S6 kinase,90kD,polypeptide 1,dJ590P13.1,EC 2.7.11.1,HU 1,HU1,KS6A1,MAP kinase activated protein kinase 1a,MAP kinase-activated protein kinase 1a,MAPK-activated protein kinase 1a,MAPKAP kinase 1a,MAPKAPK-1a,MAPKAPK1A,MGC79981,Mitogen-activated protein kinase-activated protein kinase 1A,OTTHUMP00000004113,p90 RSK1,p90-RSK 1,p90rsk,p90RSK1,p90S6K,pp90RSK1,Ribosomal protein S6 kinase 90kD 1,Ribosomal protein S6 kinase 90kD polypeptide 1,Ribosomal protein S6 kinase 90kDa polypeptide 1,Ribosomal protein S6 kinase alpha 1,Ribosomal protein S6 kinase alpha-1,Ribosomal protein S6 kinase polypeptide 1,Ribosomal S6 kinase 1,RPS6K1 alpha,rps6ka,Rps6ka1,RSK 1,RSK 1 p90,RSK,RSK-1,RSK1,S6K alpha 1,S6K-alpha-1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC,ELISA
Concentration：0.4mg/mL
Immunogen：Recombinant protein of human RPS6KA1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000, IHC 1：25-1：100
Swissprot：Q15418
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Signal transduction
