Background:RASSF7 (Ras association domain-containing protein 7), also designated HRAS1-related cluster protein 1, is a 373 amino acid protein that localizes to the centrosome. RASSF7, RASSF8, RASSF9 and RASSF10 are four evolutionary conserved proteins that are collectively known as the N-terminal RASSF family. Expressed in skin, neural tube and eye, RASSF7 is believed to play an essential role in mitosis. Further supporting its mitotic role, knockdown of Xenopus RASSF7 has been shown to influence cell failure to form mitotic spindle and also cause nuclear breakdown and apoptosis.
仕様
Synonyms:C11orf13,Chromosome 11 open reading frame 13,HRAS1,HRAS1 related cluster 1,HRAS1 related cluster protein 1,HRAS1-related cluster protein 1,HRC1,MGC126069,MGC126070,Ras association (RalGDS/AF 6) domain family (N terminal) member 7,Ras association (RalGDS/AF 6) domain family 7,Ras association domain containing protein 7,Ras association domain-containing protein 7,RASF7,RASSF 7,RASSF7
Host:Rabbit
Reactivity:Human
Applications:WB,IHC,ELISA
Concentration:0.7mg/mL
Immunogen:Recombinant protein of human RASSF7
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:500-1:2000, IHC 1:25-1:100
Swissprot:Q02833
Isotype:IgG
Research Areas:Cell Biology, Epigenetics and Nuclear Signaling