Background：RACK1 （receptor for activated C kinase 1） is a 317 amino acid G protein b subunit-like protein that functions as a RACK and inhibits the activity of Src tyrosine kinases. In response to PKC activation, the intracellular localization of RACK1 and PKC bII changes, and RACK1 and PKC bII co-localize to the same sites. RACK1 is therefore thought to be a shuttling protein for PKC bII. A deficit in RACK1 may be associated with impaired PKC activation in the aging brain.
仕様
Synonyms：Cell proliferation-inducing gene 21 protein,GBLP,Gnb2-rs1,Gnb2l1,Guanine nucleotide binding protein （G protein） beta polypeptide 2 like 1,Guanine nucleotide binding protein beta polypeptide 2 like 1,Guanine nucleotide binding protein beta subunit 2 like 1,Guanine nucleotide binding protein beta subunit like protein 12.3,Guanine nucleotide binding protein subunit beta 2 like 1,Guanine nucleotide binding protein subunit beta like protein 12.3,Guanine nucleotide-binding protein subunit beta-2-like 1,Guanine nucleotide-binding protein subunit beta-like protein 12.3,H12.3,HLC-7,Human lung cancer oncogene 7 protein,lung cancer oncogene 7,OTTHUMP00000223704,OTTHUMP00000223870,OTTHUMP00000223891,OTTHUMP00000223893,OTTHUMP00000223900,OTTHUMP00000223902,OTTHUMP00000223930,OTTHUMP00000223931,PIG21,Proliferation inducing gene 21,Protein homologous to chicken B complex protein guanine nucleotide binding,RACK1,Receptor for activated C kinase 1,Receptor for activated C kinase,Receptor of activated protein kinase C 1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,ELISA
Concentration：0.5mg/mL
Immunogen：Recombinant protein of human GNB2L1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1：1000
Swissprot：P63244
Isotype：IgG
Research Areas：Cancer, Cell Biology, Signal transduction
