Background:Poly(ADP-ribosylation) is a method of DNA damage-dependent posttranslational modification that helps to rescue injured proliferating cells from cell death. The PARP (poly(ADP-ribose) polymerase) proteins comprise a superfamily of enzymes that functionally modify histones and other nuclear proteins, thereby preventing cell death. PARPs use NAD+ as a substrate to catalytically transfer ADP-ribose residues onto protein acceptors; a process that, when repeated multiple times, leads to the formation of poly(ADPribose) chains on the protein.
仕様
Synonyms:5330431N24Rik,AI851877,C12orf6,DKFZp779H0122,HIN1L,MIB006,OTTMUSP00000027219,Poly (ADP ribose) polymerase family member 11,RGD1561791
Host:Rabbit
Reactivity:Human,Mouse
Applications:IHC,ELISA
Concentration:0.4mg/mL
Immunogen:Recombinant protein of human PARP11
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3