Background:This gene encodes a transcription factor that is a member of the nuclear receptor subfamily 1. The encoded protein is a ligand-sensitive transcription factor that negatively regulates the expression of core clock proteins. In particular this protein represses the circadian clock transcription factor aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL). This protein may also be involved in regulating genes that function in metabolic, inflammatory and cardiovascular processes.
仕様
Synonyms:EAR-1,EAR1,ERBA-related 1,hRev,Nr1d1,NR1D1,Nuclear receptor Rev ErbA alpha,Nuclear receptor subfamily 1 group D member 1,Rev erbAalpha,Rev erbalpha,Rev-erbA-alpha,Rev-ErbAalpha,Reverba,THRA1,THRAL,Thyroid hormone receptor,alpha like,Thyroid hormone receptor,alpha-1- like,V-erbA-related protein 1
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:IHC,ELISA
Concentration:0.4mg/mL
Immunogen:Recombinant protein of human NR1D1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:50-1:200
Swissprot:P20393
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Neuroscience, Signal transduction