Background：This gene encodes a protein that is a subunit of one of the complexes that forms the mitochondrial respiratory chain. This protein is one of over 40 subunits found in complex I, the nicotinamide adenine dinucleotide （NADH）：ubiquinone oxidoreductase. This complex functions in the transfer of electrons from NADH to the respiratory chain, and ubiquinone is believed to be the immediate electron acceptor for the enzyme. Mutations in this gene cause Leigh syndrome due to mitochondrial complex I deficiency, a severe neurological disorder that results in bilaterally symmetrical necrotic lesions in subcortical brain regions.
仕様
Synonyms：CI 20,CI-20kD,Complex I 20kDa subunit,Complex I mitochondrial respiratory chain 20 KD subunit,Complex I-20kD,FLJ45860,FLJ46880,MGC120002,MY017,NADH coenzyme Q reductase,NADH dehydrogenase （ubiquinone） Fe S protein 7 20kDa （NADH coenzyme Q reductase）,NADH dehydrogenase （ubiquinone） FeS protein 7,20kDa （NADHcoenzyme Q reductase）,NADH dehydrogenase （ubiquinone） FeS protein7,20kDa （NADHcoenzyme Q reductase）,NADH dehydrogenase [ubiquinone] iron-sulfur protein 7,mitochondrial,NADH-ubiquinone oxidoreductase 20 kDa subunit,NADH：ubiquinone oxidoreductase PSST subunit,NADHcoenzyme Q reductase,Ndufs7,NDUS7,PSST,PSST subunit
Host：Rabbit
Reactivity：Human,Mouse
Applications：IHC,ELISA
Concentration：0.7mg/mL
Immunogen：Recombinant protein of human NDUFS7
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：200
Swissprot：O75251
Isotype：IgG
Research Areas：Cancer, Metabolism, Neuroscience, Signal transduction
