Background:This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development.
仕様
Synonyms:D1S1733E,DAN,DAN domain family member 1,DAND 1,DAND1,Differential screening selected gene aberrant in neuroblastoma,MGC8972,NB,NBL 1,Neuroblastoma candidate region suppression of tumorigenicity 1,Neuroblastoma suppression of tumorigenicity 1,Neuroblastoma suppressor of tumorigenicity 1,NO 3,NO3,Zinc finger protein DAN
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:IHC,ELISA
Concentration:0.3mg/mL
Immunogen:Recombinant protein of human NBL1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3