Background：The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas （TNFRSF6）-associated via death domain （FADD） and MAP-kinase activating death domain-containing protein （MADD）, and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis.
仕様
Synonyms：LRDD,PIDD
Host：Rabbit
Reactivity：Human
Applications：IHC,ELISA
Concentration：0.3mg/mL
Immunogen：Recombinant protein of human PIDD1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
