Background：Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
仕様
Synonyms：Brain serine protease 1,BSP1,hK8,HNP,HPN,Kallikrein 8 （neuropsin/ovasin）,Kallikrein related peptidase 8,Kallikrein-8,Kallikrein8,KLK 8,Klk8,KLK8 protein type 1,KLK8 protein type 2,KLK8,Neuropsin,neuropsin type 1,Neuropsin type 1,included,Neuropsin type 2,Neuropsin type 2,included,Neuropsin,mouse,homolog of,NP,NRPN,Ovasin,PRO322,Protease serine 19,PRSS 19,PRSS19,Serine protease 19,Serine protease kallikrein,Serine protease kallikrein/ovasin/neuropsin,Serine protease TADG 14,Serine protease TADG-14,Serine protease TADG14,TADG 14,TADG14,Tumor associated differentially expressed gene 14,Tumor associated differentially expressed gene 14 protein,Tumor-associated differentially expressed gene 14 protein,UNQ283
Host：Rabbit
Reactivity：Human
Applications：IHC,ELISA
Concentration：0.2mg/mL
Immunogen：Recombinant protein of human KLK8
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：25-1：100
Swissprot：O60259
Isotype：IgG
Research Areas：Cancer, Cell Biology, Signal transduction
