Background:In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein.
仕様
Synonyms:Class I cytokine receptor,CRL1,Cytokine receptor-like 1,I27RA,IL-27 receptor subunit alpha,IL-27R subunit alpha,IL-27R-alpha,IL-27RA,IL27R alpha,IL27R,Il27ra,Interleukin 27 receptor alpha chain precursor,Interleukin 27 receptor,Interleukin-27 receptor subunit alpha,Protein CRL1,T cell cytokine receptor type 1,TCCR,Type 1 T cell cytokine receptor,Type I T-cell cytokine receptor,WSX-1,WSX1,ZcytoR1
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,IHC,ELISA
Concentration:0.4mg/mL
Immunogen:Recombinant protein of human IL27RA
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:200-1:1000, IHC 1:50-1:200
Swissprot:Q6UWB1
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Immunology, Signal transduction