Background：IKIP （Inhibitor of nuclear factor kappa-B kinase-interacting protein, IKK-interacting protein） is a single-pass membrane protein that shares a common promoter with APAF1. APAF1 and IKIP are both induced by X irradiation, however, the two gene products are transcribed in different directions. The IKIP gene is believed to be a target for p53 as expression of IKIP has been shown to promote apoptosis. IKIP has four known isoforms, three of which are found traversing the endoplasmic reticulum membrane. IKIP isoform 4 has a deletion of the transmembrane region which leads to a homogenous distribution of the protein within the cell. The IKIP gene products are expressed in vascular endothelial cells, while the isoform 4 has also been detected in lung, kidney, spleen, thymus and skeletal muscle.
仕様
Synonyms：FLJ31051,I kappa B kinase interacting protein,IKBIP,IKBKB interacting protein,IKIP1,IKIP2,IKIP3,IKK interacting protein,Inhibitor of nuclear factor kappa B kinase interacting protein
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.4mg/mL
Immunogen：Recombinant protein of human IKBIP
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
