Background:HSD3B1is a humangenethat encodes for a3beta-hydroxysteroid dehydrogenase/delta(5)-delta(4)isomerasetype I orhydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1. While it can carry out the same function asHSD3B2, it localizes primarily to different tissues, such as theplacentaand nonsteroidogenic tissues. Its requirement for the production ofprogesteroneby the placenta, which has a vital role in pregnancy, may be one reason why no disease based on mutations in this gene has been identified to date.
仕様
Synonyms:I,HSD3B,HSDB3,HSDB3A,SDR11E1,3BETAHSD
Host:Rabbit
Reactivity:Human
Applications:IHC,ELISA
Concentration:0.4mg/mL
Immunogen:Recombinant protein of human HSD3B1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:50-1:200
Swissprot:P14060
Isotype:IgG
Research Areas:Cancer, Metabolism, Signal transduction