Background：This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver.
仕様
Synonyms：3 alpha HSD1,3-alpha-HSD1,3-alpha-hydroxysteroid dehydrogenase type I,AK1C4,AKR1C4,Aldo keto reductase family 1 member C4,Aldo-keto reductase family 1 member C4,CDR,Chlordecone reductase,DD-4,DD4,Dihydrodiol dehydrogenase 4,HAKRA
Host：Rabbit
Reactivity：Human
Applications：WB,IHC,ELISA
Concentration：0.3mg/mL
Immunogen：Recombinant protein of human AKR1C4
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1：1000, IHC 1：25-1：100
Swissprot：P17516
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
