Background：The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat （CGG） in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure （POF1）. Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.
仕様
Synonyms：FMR 1,Fmr1,Fmr1 gene,FMR1,FMRP,Fragile X mental retardation 1,Fragile X mental retardation 1 protein,Fragile X mental retardation protein 1,Fragile X mental retardation protein,fragile X mental retardation syndrome-related protein 1,fragile X mental retardation,autosomal homolog 1,FRAXA,fxr1,MGC87458,POF,POF1,Protein FMR-1,Protein FMR1,wu：fb16f11,wu：fd18c10,zgc：66226
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.6mg/mL
Immunogen：Recombinant protein of human FMR1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：200
Swissprot：Q06787
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Neuroscience
