Background：This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. This protein is thought to have a role in the assembly of extracellular membranes. Also, this gene is down-regulated during transformation of normal myoblasts to rhabdomyosarcoma cells and the encoded protein may function as a link between presenilin-2 and an intracellular signaling pathway. Multiple alternatively spliced variants, encoding the same protein, have been identified.
仕様
Synonyms：AAG 11,AAG11,Aging associated gene 11,Down regulated in rhabdomyosarcoma LIM protein,Downregulated in rhabdomyosarcoma LIM protein,DRAL,FHL 2,FHL-2,Fhl2,FHL2 protein,FHL2,Four and a half LIM domain protein 2,Four and a half LIM domains 2,Four and a half LIM domains protein 2,KIAA0990,LIM domain protein DRAL,Skeletal muscle LIM protein 3,Skeletal muscle LIM-protein 3,SLIM 3,SLIM-3,SLIM3
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC,ELISA
Concentration：0.5mg/mL
Immunogen：Recombinant protein of human FHL2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：1000-1：5000, IHC 1：50-1：200
Swissprot：Q14192
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
