Background：The second largest human chromosome, 2 consists of 237 million bases encoding over 1,400 genes and making up approximately 8％ of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstrom syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes.
仕様
Synonyms：FAKD1,FAST kinase domain containing protein 1,FAST kinase domain-containing protein 1,FAST kinase domains 1,FASTKD1,FLJ21901,KIAA1800,OTTHUMP00000207008,OTTHUMP00000207010
Host：Rabbit
Reactivity：Human
Applications：IHC,ELISA
Concentration：0.5mg/mL
Immunogen：Recombinant protein of human FASTKD1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
