Background:This gene encodes a member of the deoxyribonuclease I family. The encoded protein hydrolyzes DNA, is not inhibited by actin, and mediates the breakdown of DNA during apoptosis. Mutations in this gene are a cause of systemic lupus erythematosus-16. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
仕様
Synonyms:Deoxyribonuclease gamma,Deoxyribonuclease I like 3,Deoxyribonuclease I like III,Deoxyribonuclease I-like 3,DHP 2,DHP2,DNAS1L3,DNase gamma,DNase I homolog protein 2,DNase I homolog protein DHP2,DNase I like 3,DNase I-like 3,DNASE1L3,DNSL3,Liver and spleen DNase,LS DNase,LS-DNase,LSD,SLEB 16,SLEB16
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,ELISA
Concentration:0.5mg/mL
Immunogen:Recombinant protein of human DNASE1L3
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:500-1:2000
Swissprot:Q13609
Isotype:IgG
Research Areas:Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism