Background：The protein encoded by this gene links endocytic vesicles to microtubules. This gene is highly expressed in Reed-Sternberg cells of Hodgkin disease. Several transcript variants encoding different isoforms have been found for this gene. Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth and microtubule bundling. Links cytoplasmic vesicles to microtubules and thereby plays an important role in intracellular vesicle trafficking. Plays a role macropinocytosis and endosome trafficking.
仕様
Synonyms：CAP GLY domain containing linker protein 1,CAP-Gly domain-containing linker protein 1,CLIP 170,CLIP,CLIP-170,CLIP1,CLIP1,CYLN1,cytoplasmic linker 1,Cytoplasmic linker protein 1,Cytoplasmic linker protein 170 alpha 2,Cytoplasmic linker protein 170 alpha-2,Cytoplasmic linker protein CLIP 170,Reed Steinberg cell expressed intermediate filament associated,Reed Sternberg intermediate filament associated protein 3,Reed-Sternberg intermediate filament-associated protein,Restin,RSN
Host：Rabbit
Reactivity：Human,Mouse
Applications：IHC,ELISA
Concentration：0.2mg/mL
Immunogen：Recombinant protein of human CLIP1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：25-1：100
Swissprot：P30622
Isotype：IgG
Research Areas：Cancer, Cell Biology, Signal transduction
