Background:This gene encodes a member of the cell death-inducing DNA fragmentation factor-like effector family. Members of this family play important roles in apoptosis. The encoded protein promotes lipid droplet formation in adipocytes and may mediate adipocyte apoptosis. This gene is regulated by insulin and its expression is positively correlated with insulin sensitivity. Mutations in this gene may contribute to insulin resistant diabetes. A pseudogene of this gene is located on the short arm of chromosome 3. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene.
仕様
Synonyms:Cell death activator,Cell death activator CIDE-3,Cell death inducing DFFA like effector C,Cell death inducing DFFA like effector protein C,Cell death-inducing DFFA-like effector protein C,CIDE 3,CIDE3,CIDEC,CIDEC,Fat specific protein 27,Fat-specific protein FSP27 homolog,FLJ20871,FPLD5,FSP27
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:IHC,ELISA
Concentration:0.3mg/mL
Immunogen:Recombinant protein of human CIDEC
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:25-1:100
Swissprot:Q96AQ7
Isotype:IgG
Research Areas:Cancer, Cell Biology, Cardiovascular, Epigenetics and Nuclear Signaling