Background：CHAC1 （ChaC, cation transport regulator homolog 1 （E. coli）） is a 264 amino acid cytoplasmic protein that belongs to the ChaC family. Induced by chemical activators of the unfolded protein response （UPR） pathway, including DTT, tunicamycin and thapsigargin, CHAC1 is a pro-apoptotic member of this pathway and may mediate the pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade. Overexpression of CHAC1 may lead to an increase in apoptosis, while suppression of CHAC1 results in subdued apoptosis.
仕様
Synonyms：Blocks Notch protein,Botch,Cation transport regulator like protein 1,Cation transport regulator-like protein 1,ChaC,ChaC cation transport regulator homolog 1,ChaC cation transport regulator like 1,chac1,CHAC1,Gamma GCT acting on glutathione homolog 1,Gamma-GCG 1,Glutathione-specific gamma-glutamylcyclotransferase 1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.7mg/mL
Immunogen：Recombinant protein of human CHAC1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
