Background：Centromere protein C 1 is a centromere autoantigen and a component of the inner kinetochore plate. The protein is required for maintaining proper kinetochore size and a timely transition to anaphase. A putative pseudogene exists on chromosome 12. Component of the CENPA-NAC （nucleosome-associated） complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD （nucleosome distal） complex and may be involved in incorporation of newly synthesized CENPA into centromeres.
仕様
Synonyms：CENP-C 1,CENP-C,CENPC,CENPC1,Centromere autoantigen C,Centromere autoantigen C1,Centromere protein C 1,Centromere protein C,hcp-4,ICEN7,Interphase centromere complex protein 7,MIF2
Host：Rabbit
Reactivity：Human
Applications：IHC,ELISA
Concentration：0.6mg/mL
Immunogen：Recombinant protein of human CENPC
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：200
Swissprot：Q03188
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
