Background：The human ASH2L gene encodes a 628 amino acid protein known as ASH2L1, or isoform 1, which contains a nuclear localization signal and PHD finger motif, suggesting that the gene product functions as a transcription regulator. Alternative splicing results in a shorter isoform 2, designated ASH2L2, which is missing the first 94 amino acid residues found in ASH2L1. Human ASH2L proteins are 60％ homologous to Drosophila ash2, which positively regulates expression of certain genes in early development, and contain similar, but not identical, domains, including a zinc finger motif. ASH2L is highly expressed in fetal liver, testis and leukemia cell lines with erythroid and megakaryocytic potential, such as K562, Hel and Dami.
仕様
Synonyms：ASH 2,Ash2 （absent small or homeotic） like,Ash2 （absent,small,or homeotic） like （Drosophila）,ASH2,ASH2 LIKE,ASH2 like protein,ASH2-like protein,Ash2l,ASH2L,ASH2L1＞,ASH2L2,Bre 2,Bre2,Discs 2-like,Drosophila absent,small,or homeotic,Drosophila ASH2-like,Set1/Ash2 histone methyltransferase complex subunit ASH2
Host：Rabbit
Reactivity：Human,Mouse
Applications：IHC,ELISA
Concentration：0.4mg/mL
Immunogen：Recombinant protein of human ASH2L
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：200
Swissprot：Q9UBL3
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
