Background:ASB-8 (ankyrin repeat and SOCS box-containing 8) is a 288 amino acid member of the ASB family that contains one SOCS box domain and four ANK repeats. Localized to the cytoplasm, ASB-8 functions as a substrate-recognition component of an E3 ubiquitin-protein ligase complex and, working in conjunction with other proteins, plays a role in the ubiquitination and subsequent proteasomal degradation of target proteins. The highest level of ASB-8 expression has been detected in skeletal muscle. ASB-8 is also expressed in heart, brain, placenta, liver, kidney and pancreas.
仕様
Synonyms:Ankyrin repeat and SOCS box containing 8,Ankyrin repeat and SOCS box protein 8,ASB 8,ASB-8,ASB8,ASB8,FLJ21255,MGC5540,OTTHUMP00000237000,OTTHUMP00000237001,OTTHUMP00000237007,OTTHUMP00000237009,OTTHUMP00000237010,PP14212
Host:Rabbit
Reactivity:Human,Mouse
Applications:IHC,ELISA
Concentration:0.7mg/mL
Immunogen:Recombinant protein of human ASB8
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3