Background：Phosphatidylinositol-5,4-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. The protein encoded by this gene is one of a family of enzymes capable of catalyzing the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. The amino acid sequence of this enzyme does not show homology to other kinases, but the recombinant protein does exhibit kinase activity. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family.
仕様
Synonyms：1 phosphatidylinositol 4 phosphate 5 kinase 2 alpha,1 phosphatidylinositol 4 phosphate 5 kinase,1 phosphatidylinositol 4 phosphate kinase,1-phosphatidylinositol-5-phosphate 4-kinase 2-alpha,4 5 kinase B isoform,4 5 kinase C isoform,4 5 kinase isoform 2 alpha,Diphosphoinositide kinase 2 alpha,Diphosphoinositide kinase 2-alpha,FLJ13267,Phosphatidylinositol 4 phosphate 5 kinase type 2 alpha,Phosphatidylinositol 4 phosphate 5 kinase type II alpha,Phosphatidylinositol-5-phosphate 4-kinase type II alpha,Phosphatidylinositol-5-phosphate 4-kinase type-2 alpha,PI（5）P 4-kinase type II alpha,PI42A,PI5P4KA,PIP4K2A,PIP4KII-alpha,PIP5K2,PIP5K2A,PIP5KII alpha,PIP5KII-alpha,PIP5KIIA,PIP5KIII,PIPK,PtdIns,PtdIns（4）P-5-kinase B isoform,PtdIns（4）P-5-kinase C isoform,PtdIns（5）P-4-kinase isoform 2-alpha,Type II phosphatidylinositol 4 phosphate 5 kinase 53 K isoform
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC,ELISA
Concentration：0.3mg/mL
Immunogen：Recombinant protein of human PIP4K2A
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000, IHC 1：50-1：200
Swissprot：P48426
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
