Background:Caprin-1is aproteinthat in humans is encoded by theCAPRIN1gene. May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. May form homomultimers. Directly interacts with G3BP1 in cytoplasmic RNA granules. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs.
仕様
Synonyms:activation/proliferation-associated protein 1,CAPR1,Caprin-1,CAPRIN1,Cell cycle-associated protein 1,Cytoplasmic activation- and proliferation-associated protein 1,cytoplasmic activation/proliferation-associated protein-1,GPI-anchored membrane protein 1,GPI-anchored protein p137,GPI-p137,GPIAP1,M11S1,Membrane component chromosome 11 surface marker 1,p137GPI,RNA granule protein 105,RNG105
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,ELISA
Concentration:0.2mg/mL
Immunogen:Recombinant protein of human CAPRIN1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3