Background：Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus; the remainder of the protein is identical among all the isoforms.
仕様
Synonyms：BB404130,Brain form hexokinase,dea,DrHXK1,EC 2.7.1.1,Glycolytic enzyme,HEXOKIN,hexokinase I,Hexokinase PI,Hexokinase type I,Hexokinase,tumor isozyme,Hexokinase-1,Hexokinase-A,HK I,HK1,HK1 tb,Hk1-s,HK1-ta,HK1-tb,HK1-tc,HKD,HKI,HMSNR,HXK1,HXK1,im：7148527,mHk1-s,wu：fc09d08,wu：fc16e02,wu：fc21e02,wu：fq14b11,zgc：55790,zgc：77618
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.4mg/mL
Immunogen：Recombinant protein of human HK1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：200
Swissprot：P19367
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Metabolism, Signal transduction
