Background：Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
仕様
Synonyms：DKFZp686M1669,Hexokinase 2,Hexokinase 2 muscle,Hexokinase type II,Hexokinase-2,HK 2,HK II,HK2,HKII,HxK 2,HxK2,HXK2,Muscle form hexokinase
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.4mg/mL
Immunogen：Recombinant protein of human HK2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：200
Swissprot：P52789
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Metabolism, Signal transduction
