Background:Cytokine-inducible kinase is a putative serine/threonine kinase. CNK contains both a catalytic domain and a putative regulatory domain. It may play a role in regulation of cell cycle progression and tumorigenesis. Serine/threonine-protein kinase involved in cell cycle regulation, response to stress and Golgi disassembly. Polo-like kinases act by binding and phosphorylating proteins are that already phosphorylated on a specific motif recognized by the POLO box domains. Phosphorylates ATF2, BCL2L1, CDC25A, CDC25C, CHEK2, HIF1A, JUN, p53/TP53, p73/TP73, PTEN, TOP2A and VRK1.
仕様
Synonyms:CNK,Cytokine Inducible Kinase,Cytokine-inducible serine/threonine-protein kinase,FGF inducible kinase,FGF-inducible kinase,FNK,PLK-3,Plk3,PLK3,Polo Like Kinase 3,Polo-like kinase 3,PRK,Proliferation Related Kinase,Proliferation-related kinase,Serine/threonine-protein kinase PLK3
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:IHC,ELISA
Concentration:0.2mg/mL
Immunogen:Recombinant protein of human PLK3
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3