Background:The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.
仕様
Synonyms:B lymphocyte serine/threonine protein kinase,B lymphocyte serine/threonine-protein kinase,BL44,GC kinase,GCK,Germinal center kinase,germinal centre kinase (GC kinase),M4K2,Map4k2,MAPK/ERK kinase kinase kinase 2,MEK kinase kinase 2,MEKKK 2,Mitogen activated protein kinase kinase kinase kinase 2,Mitogen-activated protein kinase kinase kinase kinase 2,Rab8 interacting protein,Rab8 interacting protein,formerly,Rab8-interacting protein,RAB8IP,RAB8IP,formerly
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,ELISA
Concentration:0.3mg/mL
Immunogen:Recombinant protein of human MAP4K2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3