Background:This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms:Human ZW10 interacting protein 1,HZwint 1,HZwint1,KNTC 2 AP,KNTC2AP,MGC 117174,MGC117174,ZW10 interacting kinetochore protein,ZW10 interacting protein 1,ZW10 interactor,ZW10 interactor,kinetochore protein,ZW10-interacting protein 1,ZWINT 1,ZWINT,Zwint-1,ZWINT,ZWINT1
Host:Rabbit
Reactivity:Human
Applications:IHC,ELISA
Concentration:0.5mg/mL
Immunogen:Recombinant protein of human ZWINT
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:50-1:200
Swissprot:O95229
Isotype:IgG
Research Areas:Cell Biology, Epigenetics and Nuclear Signaling