Background:Epidermal growth factor receptor substrate 15-like 1is aproteinthat in humans is encoded by theEPS15L1gene. Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. Interacts with EPS15, AGFG1/HRB and AGFG2/HRBL. Associates with the clathrin-associated adapter protein complex 2 (AP-2) By similarity. Interacts with FCHO1. Interacts with FCHO2. Interacts (via EH domains) with DAB2.
仕様
Synonyms:EP15R,epidermal growth factor receptor pathway substrate 15- ike 1,Epidermal growth factor receptor substrate 15 like 1,Epidermal growth factor receptor substrate 15-like 1,epidermal growth factor receptor substrate EPS15R,Eps15 related protein,Eps15-related protein,EPS15L1,Eps15R
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,IHC,ELISA
Concentration:0.1mg/mL
Immunogen:Recombinant protein of human EPS15L1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3