Background：This gene encodes a member of the toll-like receptor （TLR） family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.
仕様
Synonyms：FLJ10052,MGC126430,MGC126431,SLEB1,TIL 3,TIL3,TLR 5,Tlr5,TLR5,Toll like receptor 5,Toll like receptor 5 precursor,Toll-like receptor 5,Toll/interleukin 1 receptor like protein 3,Toll/interleukin-1 receptor-like protein 3
Host：Rabbit
Reactivity：Human
Applications：IHC,ELISA
Concentration：0.3mg/mL
Immunogen：Recombinant protein of human TLR5
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
