Background:C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks. Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro.
仕様
Synonyms:2010301N04Rik,AI452191,Aplf,APLF,Aprataxin and PNK-like factor,Apurinic-apyrimidinic endonuclease APLF,C2orf13,PNK and APTX like FHA protein,PNK and APTX-like FHA domain-containing protein,RGD1565557,XIP1,XRCC1 interacting protein 1,XRCC1-interacting protein 1
Host:Rabbit
Reactivity:Human
Applications:IHC,ELISA
Concentration:0.5mg/mL
Immunogen:Recombinant protein of human APLF
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3