Background：This gene encodes the receptor for the anti-Mullerian hormone （AMH） which, in addition to testosterone, results in male sex differentiation. AMH and testosterone are produced in the testes by different cells and have different effects. Testosterone promotes the development of male genitalia while the binding of AMH to the encoded receptor prevents the development of the mullerian ducts into uterus and Fallopian tubes. Mutations in this gene are associated with persistent Mullerian duct syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified.
仕様
Synonyms：AMH type II receptor,AMHR,AMHR2,AMHR2,Anti Mullerian hormone receptor,type II,Anti-Muellerian hormone type II receptor,Anti-Muellerian hormone type-2 receptor,MGC141312,MIS type II receptor,MISR2,MISRII,MRII,Muellerian hormone type 2 receptor,Muellerian hormone type II receptor,Muellerian inhibiting substance type II receptor,Mullerian hormone receptor type II,Mullerian inhibiting substance type II receptor
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.3mg/mL
Immunogen：Recombinant protein of human AMHR2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：200
Swissprot：Q16671
Isotype：IgG
Research Areas：Cancer, Signal transduction, Stem cells
