Background:This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants.
仕様
Synonyms:ACO11,ACOT 11,ACOT11,Acyl CoA thioester hydrolase 11,Acyl CoA thioesterase 11,Acyl coenzyme A thioesterase 11,Acyl-CoA thioester hydrolase 11,Acyl-CoA thioesterase 11,Acyl-coenzyme A thioesterase 11,Adipose associated thioesterase,Adipose-associated thioesterase,BFIT 1,BFIT 2,BFIT,BFIT1,BFIT2,Brown fat inducible thioesterase,Brown fat-inducible thioesterase,KIAA0707,OTTHUMP00000046722,StAR related lipid transfer (START) domain containing 14,STARD 14,STARD14,START domain containing 14,THEA,THEM 1,THEM1,Thioesterase adipose associated,Thioesterase superfamily member 1
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,ELISA
Concentration:0.3mg/mL
Immunogen:Recombinant protein of human ACOT11
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:200-1:1000
Swissprot:Q8WXI4
Isotype:IgG
Research Areas:Cardiovascular, Metabolism, Signal transduction