Background:Prostaglandin E synthase 3 (cytosolic)is anenzymethat in humans is encoded by the PTGES3gene. The protein encoded by this gene is also known as p23 which functions as a chaperone which is required for proper functioning of the glucocorticoid and other steroid receptors. Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes.
仕様
Synonyms:Co chaperone p23,cPGES,Cytosolic prostaglandin E synthase,Cytosolic prostaglandin E2 synthase,Hsp90 co chaperone,Hsp90 co-chaperone,P23,Progesterone receptor complex,Progesterone receptor complex p23,Prostaglandin E synthase 3 (cytosolic),Prostaglandin E synthase 3,PTGES 3,PTGES3,Sid 3177,TEBP,TEBP,Telomerase binding protein p23,Telomerase-binding protein p23,Unactive progesterone receptor 23 kD
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:IHC,ELISA
Concentration:0.2mg/mL
Immunogen:Recombinant protein of human PTGES3
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:25-1:100
Swissprot:Q15185
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Metabolism, Signal transduction