Background:The innate immune system confers host defense against viral and microbial infection, and TRAFD1 is a negative feedback regulator that controls excessive immune responses. Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation.
仕様
Synonyms:FLN29,FLN29 gene product,Protein FLN29,TRAD1,TRAF type zinc finger domain containing 1,TRAF type zinc finger domain containing protein 1,TRAF-type zinc finger domain-containing protein 1,TRAFD 1,TRAFD1
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,ELISA
Concentration:0.3mg/mL
Immunogen:Recombinant protein of human TRAFD1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3