Background：This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins （tumor necrosis factor receptor-associated factors） and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.
仕様
Synonyms：Act 1,ACT1,Activator of cAMP responsive element modulator （CREM） in testis,Adapter protein CIKS,C6ORF4,C6ORF5,C6ORF6,Chromosome 6 Open Reading Frame 4,Chromosome 6 Open Reading Frame 5,Chromosome 6 Open Reading Frame 6,CIKS,Connection to IKK and SAPK / JNK,Connection to IKK and SAPK/JNK,Nuclear Factor Kappa B Activator 1,Nuclear factor NF kappa B activator 1,Nuclear factor NF-kappa-B activator 1,TRAF3 interacting protein 2,TRAF3-interacting protein 2,TRAF31P2,TRAF3IP2
Host：Rabbit
Reactivity：Human
Applications：WB,IHC,ELISA
Concentration：0.3mg/mL
Immunogen：Recombinant protein of human TRAF3IP2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1：1000, IHC 1：25-1：100
Swissprot：O43734
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Signal transduction
