Background:This gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion.
仕様
Synonyms:AA517111,Basement membrane protein 40,Basement-membrane protein 40,BM 40,BM-40,BM40,Cysteine rich protein,hm:zeh0062,MGC128090,OI17,ON,Osteonectin,Secreted acidic cystein rich glycoprotein,Secreted protein acidic and cysteine rich,Secreted protein acidic and rich in cysteine,Secreted protein acidic cysteine rich (osteonectin),Secreted protein acidic cysteine rich,SPARC,SPRC,SPRC
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,ELISA
Concentration:0.3mg/mL
Immunogen:Recombinant protein of human SPARC
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:500-1:2000
Swissprot:P09486
Isotype:IgG
Research Areas:Cancer, Cell Biology, Cardiovascular, Developmental biology, Signal transduction, Stem cells