Background：This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins witHuman, Mouseono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：2810449N18Rik,AI043036,Mono ADP ribosyltransferase sirtuin 6,NAD-dependent protein deacetylase sirtuin-6,Regulatory protein SIR2 homolog 6,Regulatory protein SIR2 homolog,SIR2 like 6,SIR2 like protein 6,Sir2 related protein type 6,SIR2-like protein 6,SIR2L6,SIR6,SIRT 6,SIRT6,Sirtuin （silent mating type information regulation 2 homolog） 6 （S. cerevisiae）,Sirtuin 6,Sirtuin type 6,Sirtuin6
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,ELISA
Concentration：0.2mg/mL
Immunogen：Recombinant protein of human SIRT6
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000
Swissprot：Q8N6T7
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Signal transduction
