Background：Adrenergic receptors （ARs） include four general types （a1, a2, b1 and b2） that are found in different target tissues and differ in their affinities and responses to various agonists and antagonists. The coupling of ARs to specific intracellular effectors is mediated through diverse heterotrimeric G proteins. ARs play a critical role in the development of prostate cancer, and transcriptional activity of AR is partly regulated by coregulatory proteins. RAD54L2 （RAD54-like 2）, also known as ARIP4 （androgen receptor-interacting protein 4）, HSPC325 or SRISNF2L, is a 1,467 amino acid nuclear protein belonging to the SNF2/RAD54 helicase family that consists of one helicase ATP-binding domain and a helicase C-terminal domain. RAD54L2 is a DNA helicase that regulates androgen receptor （AR）-dependent transactivation in a promoter-dependent manner. RAD54L2 is post-translationally sumoylated or phosphorylated upon DNA damage.
仕様
Synonyms：Androgen receptor interacting protein 4,Androgen receptor-interacting protein 4,Arip4,ARIP4,HCMV interacting protein;,Helicase ARIP4,HSPC325,RAD54 like 2 （S. cerevisiae）,RAD54 like protein 2,RAD54-like protein 2,Rad54l2,SRISNF2L,Steroid receptor interacting SNF2 domain protein
Host：Rabbit
Reactivity：Human,Mouse
Applications：IHC,ELISA
Concentration：0.6mg/mL
Immunogen：Recombinant protein of human RAD54L2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：200
Swissprot：Q9Y4B4
Isotype：IgG
Research Areas：Epigenetics and Nuclear Signaling, Signal transduction
