Background：Protein arginine methyltransferase 7is aproteinthat in humans is encoded by thePRMT7gene.Argininemethylationis an apparently irreversible protein modification catalyzed by arginine methyltransferases, such as PMT7, usingS-adenosylmethionine（AdoMet） as the methyl donor. Arginine methylation is implicated insignal transduction, RNA transport, andRNA splicing. May be involved in etoposide-induced cytotoxicity, a chemotherapeutic agent frequently used for testicular cancer and small-cell lung cancer that can cause cytotoxicity in the treatment of other cancers. Down-regulation confers increased sensitivity to the Top1 inhibitor camptothecin （CPT）.
仕様
Synonyms：[Myelin basic protein]-arginine N-methyltransferase PRMT7,ANM7,FLJ10640,Histone-arginine N-methyltransferase PRMT7,KIAA1933,Myelin basic protein arginine N methyltransferase,OTTHUMP00000174863,PRMT7,Protein arginine methyltransferase 7,Protein arginine N-methyltransferase 7
Host：Rabbit
Reactivity：Human
Applications：WB,ELISA
Concentration：0.2mg/mL
Immunogen：Recombinant protein of human PRMT7
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000
Swissprot：Q9NVM4
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
