Background：Protein arginine N-methyltransferase 2is anenzymethat in humans is encoded by thePRMT2gene. Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4. Acts as a coactivator （with NCOA2） of the androgen receptor （AR）-mediated transactivation. Acts as a coactivator （with estrogen） of estrogen receptor （ER）-mediated transactivation. Enhances PGR, PPARG, RARA-mediated transactivation. May inhibit NF-kappa-B transcription and promote apoptosis. Represses E2F1 transcriptional activity （in a RB1-dependent manner）. May be involved in growth regulation.
仕様
Synonyms：ANM2,EC 2.1.1.,histone arginine N methyltransferase PRMT2,Histone-arginine N-methyltransferase PRMT2,HMT 1,HMT1 （hnRNP methyltransferase S. cerevisiae） like 1,HMT1,HMT1 hnRNP methyltransferase like 1,hnRNP methyltransferase （S. cerevisiae） like 1,hnRNP methyltransferase like 1,Hrmt1l1,MGC111373,PRMT 2,PRMT2 alpha,prmt2,PRMT2 beta,PRMT2 gamma,PRMT2 protein,PRMT2L2,Protein arginine methyltransferase 2,Protein arginine N methyltransferase 2,Protein arginine N-methyltransferase 2,Zf2
Host：Rabbit
Reactivity：Human
Applications：IHC,ELISA
Concentration：0.2mg/mL
Immunogen：Recombinant protein of human PRMT2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
