Background:Phosphatidylethanolamine-binding protein 1is aproteinthat in humans is encoded by thePEBP1gene. Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase By similarity. Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation.
仕様
Synonyms:Epididymis luminal protein 210,Epididymis secretory protein Li 34,Epididymis secretory protein Li 96,HCNP,HCNPpp,HEL 210,HEL S 34,HEL S 96,Hippocampal cholinergic neurostimulating peptide,Neuropolypeptide h3,PBP,PEBP,PEBP 1,PEBP-1,Pebp1,PEBP1,Phosphatidylethanolamine binding protein,Phosphatidylethanolamine binding protein 1,Prostatic binding protein,Prostatic-binding protein,R kip,Raf kinase inhibitor protein,Raf kinase inhibitory protein,RKIP
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,ELISA
Concentration:0.3mg/mL
Immunogen:Recombinant protein of human PEBP1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:500-1:2000, IHC 1:50-1:200
Swissprot:P30086
Isotype:IgG
Research Areas:Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Neuroscience