Background：This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.
仕様
Synonyms：CADH3,Cadherin 3,Cadherin 3 precursor,Cadherin 3 type 1,Cadherin-3,Cadp,Calcium dependent adhesion protein placental,CDH 3,CDH3,CDH3 protein,CDHP,HJMD,P cadherin （placental）,P-cadherin,PCAD,Placental cadherin
Host：Rabbit
Reactivity：Human
Applications：WB,ELISA
Concentration：0.1mg/mL
Immunogen：Recombinant protein of human CDH3
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1：1000
Swissprot：P22223
Isotype：IgG
Research Areas：Cancer, Neuroscience, Signal transduction
