Background:This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined.
仕様
Synonyms:p53 like transcription factor,p53 related protein,p53-like transcription factor,p53-related protein,p73,P73,TP73,Tumor protein p73
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,ELISA
Concentration:0.2mg/mL
Immunogen:Recombinant protein of human TP73
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:200-1:1000
Swissprot:O15350
Isotype:IgG
Research Areas:Cancer, Cell Biology, Epigenetics and Nuclear Signaling