Background：This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t（6;22）（p21;q12）, has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG （CUG） start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.
仕様
Synonyms：Octamer binding transcription factor 4,MGC22487,Oct 3,Oct 4,Oct-3,Oct-4,OCT3,Oct4,Octamer binding protein 3,Octamer binding protein 4,Octamer binding transcription factor 3,Octamer-binding protein 3,Octamer-binding protein 4,Octamer-binding transcription factor 3,OTF 3,OTF 4,OTF-3,OTF3,OTF4,PO5F1,POU class 5 homeobox 1,POU domain class 5 transcription factor 1,POU domain transcription factor OCT4,POU domain,class 5,transcription factor 1,POU-type homeodomain-containing DNA-binding protein,POU5F1
Host：Rabbit
Reactivity：Human
Applications：WB,IHC,ELISA
Concentration：0.2mg/mL
Immunogen：Recombinant protein of human POU5F1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000, IHC 1：50-1：200
Swissprot：Q01860
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Developmental biology, Stem cells
